Postdoctoral Researcher in Cholestatic Liver Diseases

The University of Gothenburg meets societal challenges with versatile knowledge. 56,000 students and 6,600 employees make the university a large and inspiring workplace. Strong research and attractive education attract researchers and students from around the world. With new knowledge and new perspectives, the University of Gothenburg contributes to a better future.

The Department of Medicine, Division of Molecular and Clinical Medicine, conducts translational research primarily on metabolism, diabetes, liver, obesity, and cardiovascular disease to improve health and healthcare in society. The overarching goal is to create an excellent translational research environment of very high international standard.

Cholestatic liver diseases are a group of chronic liver diseases characterized by reduced bile flow from the liver (cholestasis). The etiology and pathophysiology behind cholestatic liver diseases are still not fully understood. In recent years, several studies have shown that an environmental factor, gut bacteria, is involved in the development of various liver diseases. Metabolites produced by gut bacteria from diet can affect liver function. In this project, we want to investigate whether changes in gut flora can lead to changes in metabolites and, ultimately, to the development of cholestatic liver diseases. We aim to study the role of metabolites in the development of inflammation and scar tissue (fibrosis) in bile ducts as seen in cholestatic liver diseases.

A long-term goal of the research is to identify the metabolites that are harmful to liver diseases and prevent their production by bacteria.

We hope you want to become part of our multidisciplinary research group. You are warmly welcome to apply!

Job Responsibilities

As a postdoctoral researcher, you will work with in vivo and in vitro models of cholestatic liver diseases and test whether specific metabolites play an important role in causing liver damage. This will involve using various techniques to characterize liver damage (immunohistochemistry, qPCR, western blot). You will be involved in all parts of the project, from cell culture/animal dietary experiments to data analysis under supervision.

Qualifications

Requirements:
Master's degree in molecular biology, biochemistry, or equivalent.

Previous laboratory experience.

Desirable:
Experience in:

• research in metabolism, gastrointestinal diseases
• immunohistochemistry, qPCR, Western blot
• working with cell and animal models
• working in an international research environment with English as the working language

Personal Attributes

We are looking for someone who is structured and quality-conscious in their work, but also flexible and proactive, with good problem-solving and analytical skills. Good collaboration and communication skills in English, both spoken and written, are also central to the role. We place great importance on personal suitability.

Employment

Employment type: Fixed-term employment, 6 months
Extent: 100 %
Location: Department of Medicine, Gothenburg
Start date: As soon as possible or by agreement

Contact Information for the Position

Antonio Molinaro
Assistant Professor
031-3430476
[email protected]

Malin Levin
Department Head
[email protected]

Trade Union Organizations

Trade union representatives at the University of Gothenburg can be found here: trade union representatives (https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande)

Application

You apply for the position via the University of Gothenburg's recruitment portal by registering your application electronically through the website: recruitment portal (https://www.gu.se/om-universitetet/jobba-hos-oss/lediga-anstallningar). As an applicant, you are responsible for ensuring that your application is complete in accordance with the advertisement and that it is submitted to the university no later than the application deadline.

Please include:

• Degree certificate for master's degree
• CV, including two references
• Cover letter

The application must be received by: 2025-02-06

The university actively works for a work environment with equal conditions and values the qualities that diversity brings to the organization.

The university applies individual salary setting.

According to the National Archives' regulations, the university is obliged to store application documents for two years after the appointment decision. If you, as an applicant for a position, specifically request the return of your documents, they will be returned after the two years have passed; otherwise, they will be discarded.

To staffing and recruitment companies and to you as a seller: The University of Gothenburg hires contracted advertising agencies in connection with recruitment of staff. We kindly but firmly decline direct contact with staffing and recruitment companies as well as sellers of job advertisements.