Vacant job

Are you interested in exploring fundamental mechanisms in genomics, supported by knowledgeable and supportive colleagues in an international environment? Are you looking for an employer who invests in a sustainable working life and offers secure and advantageous working conditions? We welcome you to apply for a postdoctoral position at Uppsala University.

The Department of Cell and Molecular Biology is organized into seven research programs, all focusing on different areas within cell and molecular biology: computational biology and bioinformatics, microbiology and immunology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology, and structural biology. The scientific foundation of our activities lies within biology, but our research also overlaps with other fields such as medicine, computer science, mathematics, chemistry, engineering, and physics. In total, we have over 200 employees and approximately 60 doctoral students. Read more about the department's activities at https://icm.uu.se (https://icm.uu.se).

The Deindl Lab offers an stimulating interdisciplinary environment where you will work closely with experts in biophysics, biochemistry, structural biology, and molecular biology. Our overarching goal is to investigate the molecular mechanisms underlying genome-interacting processes, using a strong interdisciplinary approach that combines structural biology, including cryo-electron microscopy, with advanced imaging, biophysical analysis, and biochemical reconstitution. For more information about the research in the Deindl Laboratory, visit http://www.deindl-lab.com/ (http://www.deindl-lab.com/).

Job Responsibilities

The postdoctoral researcher will investigate fundamental mechanisms governing chromatin organization and maintenance. The project offers a unique opportunity to use state-of-the-art cryo-electron microscopy, together with biochemical and biophysical methods, to clarify how chromatin-associated molecular machines interact with, restructure, and regulate the genome. The successful candidate will work at the interface of structural biology, molecular biology, and biochemistry to address central questions regarding chromatin architecture and gene regulation.

The postdoctoral researcher will become part of a dynamic structural biology environment at the department, with excellent access to state-of-the-art cryo-EM facilities, technical expertise, and infrastructure.

Qualifications

We are looking for a highly motivated candidate with a PhD in structural biology, biophysics, biochemistry, molecular biology, or a related field. Applicants should have prior experience in structural biology, such as cryo-electron microscopy, X-ray crystallography, NMR spectroscopy, integrative structural biology, or related methods. The PhD must be completed no later than at the time of the employment decision. In accordance with eligibility requirements, candidates who have obtained their PhD no more than three years before the application deadline will be prioritized. The three-year period is calculated from the application deadline and can be extended in cases of documented special circumstances, such as sick leave, parental leave, or trade union assignments.

The candidate must be able to work independently, and very good knowledge of English is required, as the position is located in an international research environment. We value personal qualities such as good teamwork skills, self-motivation, scientific curiosity, and a genuine interest in basic research, particularly in answering fundamental biological questions using structural, biochemical, and quantitative approaches.

Desirable/Additional Qualifications

Experience with cryo-electron microscopy, in vitro biochemical reconstitution, and biophysical analysis is highly desirable. Experience with protein purification, protein-DNA complexes, chromatin- or nucleosome-based systems, cryo-EM sample preparation, data processing, structure determination, or complementary biophysical methods will be considered an advantage.

About the Position

The employment is fixed-term for two years with the possibility of extension to three years in accordance with the Swedish Higher Education Ordinance (Chapter 5, Section 7). The position is full-time (100%). Start date: as soon as possible or by agreement. Location: Uppsala.

For further information about the position, please contact: Sebastian Deindl, [email protected].

Please submit your application by June 15, 2026, Ref: UFV-PA 2026/1515.

Uppsala University is a broad research university with strong international standing. Our ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,500 employees and 53,000 students who, with curiosity and engagement, make Uppsala University one of the most exciting workplaces in the country.

Read more about our benefits and what it is like to work at Uppsala University: https://uu.se/om-uu/jobba-hos-oss/ (https://uu.se/om-uu/jobba-hos-oss/)

The position may be subject to a security clearance. If a security clearance is required, approval is a prerequisite for employment.

We decline offers of recruitment and advertising assistance.

Applications are received through Uppsala University's recruitment system.

Union Representatives: Saco-S - [email protected], Seko - [email protected], ST (OFR/S) - [email protected]