Vacant job

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focused on, among other things, cancer, genetic, and autoimmune diseases. A key driving force at the department is to stimulate translational research and thereby promote closer collaboration between medical research and healthcare. Research is conducted within six research programs: cancer precision medicine, cancer immunotherapy, genomics and neurobiology, molecular tools and functional genomics, neuro-oncology and neurodegeneration, and vascular biology. Parts of the activity are also integrated with the departments of oncology, clinical genetics, clinical immunology, clinical pathology, and hospital physics at Uppsala University Hospital. The department has teaching assignments on several program courses, standalone courses, and international master's programs within the Faculty of Medicine. The department has a turnover of approximately 550 million SEK, of which about two-thirds are external research grants. The number of employees is approximately 400, of which about 100 are doctoral students, and there are in total over 850 active staff members. Read more about the department's activities here: www.uu.se/medarbetare/institution/immunologi-genetik-och-patologi (https://www.uu.se/medarbetare/institution/immunologi-genetik-och-patologi)

Job Description

You will use advanced genome editing methods to introduce and study hereditary or acquired mutations in colorectal cancer genes and in genes that are potential targets for drug treatment aimed at loss of heterozygosity. The work will primarily be carried out using the CRISPR-Select method. You will investigate the effect of mutations on cells growing in 3D and 2D. You will characterize cellular effects and phenotypes of the mutations using methods such as Western Blotting, FACS analysis, trans-well migration assays, viability assays, and confocal microscopy.

Qualifications

Master's degree in molecular medicine, genetics, or equivalent.

Desirable/Additional Merits

Experience in cell culture of colorectal cancer cells, experience with the CRISPR-SELECT method, Western Blotting, FACS analysis, PCR, and viability assays.

About the Position

The position is fixed-term for 12 months. Full-time. Start date by agreement. Location: Uppsala.

For further information about the position, please contact: Tobias Sjöblom, [email protected] (mailto:[email protected])

Please submit your application by August 17, 2026, Ref: UFV-PA 2026/2004

Uppsala University is a broad research university with a strong international standing. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,500 employees and 53,000 students who, with curiosity and engagement, make Uppsala University one of the most exciting workplaces in the country.

Read more about our benefits and what it is like to work at Uppsala University: https://uu.se/om-uu/jobba-hos-oss/ (https://uu.se/om-uu/jobba-hos-oss/)

The position may be subject to a security clearance. A prerequisite for employment in the case of a security clearance is that the applicant is approved.

We decline offers of recruitment and advertising assistance.

Applications are received through Uppsala University's recruitment system.

Union Representatives: Saco-S - [email protected] (mailto:[email protected]), Seko - [email protected] (mailto:[email protected]), ST (OFR/S) - [email protected] (mailto:[email protected])

Open to all. We focus on your competence, not your other prerequisites. We are open to adapting the role or workplace to your needs.