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Project Description

Doctoral Subject: Biotechnology

This doctoral project develops new methods to reconstruct spatial organization in tissues from single-cell RNA sequencing data using graph theory and machine learning. The work focuses on algorithm development and analysis of large-scale data. You will be based in the Molecular Programming group at KTH/SciLifeLab and work together with leading research groups in single-cell genomics, spatial biology, and machine learning. The position is aimed at candidates with a background in computation, applied mathematics, or related fields.

The position is part of the research school within DDLS (Data Driven Life Science). Data-driven life science (DDLS) uses data, computational methods, and AI/ML to study biological systems and processes, from molecular structures and cellular processes to human health and global ecosystems. SciLifeLab and the Wallenberg National Program for Data-Driven Life Science (DDLS) aim to train the next generation of data-driven life science researchers and to create globally leading competence in computational and data science in Sweden. The program is funded with a total of 3.3 billion SEK over 12 years by the Knut and Alice Wallenberg Foundation.

During the program, over 260 doctoral students and 200 postdocs will be part of the research school. The DDLS program has four strategic research areas: cell and molecular biology, evolution and biodiversity, precision medicine and diagnostics, and epidemiology and infection biology. For more information, see https://www.scilifelab.se/data-driven/ddls-research-school/ (https://www.scilifelab.se/data-driven/ddls-research-school/). The future of life science is data-driven. Do you want to be part of this development? Then you are welcome to apply to this unique program.

At KTH, we are now advertising a doctoral position within DDLS with a focus on data-driven cell and molecular biology. This area encompasses research that fundamentally changes our understanding of how cells function by studying their molecular components in time and space, from individual molecules to natural tissue environments.

Supervision: Ian Hoffecker, together with Stefania Giacomello, Rickard Sandberg, and Simon Koplev, are proposed to supervise the doctoral student. Decisions are made at the time of admission.

Admission Requirements

To be admitted to doctoral studies (Chapter 7, Section 39 of the Higher Education Ordinance), the applicant must have basic eligibility:

• completed an advanced level degree, or
• completed course requirements of at least 240 higher education credits, of which at least 60 higher education credits at advanced level, or
• acquired in other ways, within or outside the country, substantially equivalent knowledge.

In addition to the above, there is also a mandatory requirement for English equivalent to English B/6.

Selection

To succeed in your doctoral studies at KTH, you need to be goal-oriented and persistent in your work. In the selection of applicants, the ability to:

• independently drive your work forward,
• collaborate with others,
• have a professional attitude, and
• analyze and work with complex issues.

After the eligibility requirements, great weight will be placed on personal qualities.

Final Degree: Doctorate

Information about admission and employment

Only those admitted to doctoral studies may be employed as doctoral students. The total employment period may not be longer than what corresponds to full-time doctoral education over four years. An employed doctoral student may, to a limited extent (maximum 20%), perform certain tasks within, for example, education and administration. A new employment as a doctoral student is valid for a maximum of one year; the employment may thereafter be renewed for a maximum of two years at a time.

As a doctoral student, you will receive KTH's employment benefits and have a monthly salary according to KTH's agreement for doctoral salaries. Read more about Doctoral Studies at KTH (#).

Union Representatives

Contact details for union representatives.

Doctoral Student Section (Student Union of the Royal Institute of Technology)

Contact details for the doctoral student section.

Application

You apply via KTH's recruitment system. As an applicant, you are primarily responsible for ensuring your application is complete when submitted.

The application should contain the following:

• Copies of degree certificates and transcripts from previous university studies and certificates of fulfilled language requirements (see above). Translations to English or Swedish if the original document is not issued in one of these languages. Copies of originals must be certified.
• CV with relevant professional experience and skills.
• Cover letter with a brief account of why you wish to pursue doctoral studies, your academic interests, and how they relate to your previous studies and future goals. (Max 2 pages)
• Representative publications or technical reports. For longer documents, please attach an abstract and a web link to the full text.

The application must be received by KTH no later than the last day of application at midnight, CET/CEST (Central European Time/Central European Summer Time).

Other

For information on the processing of personal data in connection with recruitment.

It may occur that an employment at KTH is classified as security-classified. If this is the case for this specific position, a security clearance check will be conducted on the applicant in accordance with the Security Protection Act (2018:585) with consent. In these cases, a condition for employment is that the applicant is approved after the security clearance check.

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