PhD Position in Regulatory Science

The Department of Pharmaceutical Biosciences is an interdisciplinary environment where 10 research areas work to contribute to better medicines and a healthier world.

With laboratories in the heart of Uppsala Biomedical Center and Sweden's only Faculty of Pharmacy, we are a vital engine in the development of education and research within the pharmaceutical sciences. More information about the department and its activities can be found at http://www.uu.se/farmbio (http://www.uu.se/farmbio).

The announced PhD position is linked to the Graduate School in Regulatory Science, a new initiative at the Faculty of Pharmacy. Regulatory science can be defined as the science of developing and applying new tools, standards, and methods to assess the safety, efficacy, quality, and performance of products regulated by governmental or international authorities. The Graduate School aims to establish and then strengthen the faculty's role as a leading competence center by educating PhDs with integrated research and regulatory expertise in strategic collaborations with authorities, industry, and international research environments. The long-term goal is to contribute to ensuring that the population has access to safe and effective medicines.

Job Responsibilities

The PhD project will extensively address regulatory scientific aspects of tablet splitting from the perspective of rational formulation, quality control, and physiologically based biopharmaceutical modeling (PBBM), focusing on drugs with a narrow therapeutic window (NTI). Clinically, individualized treatments involving off-label use and dose adjustment of NTI drugs present complex regulatory challenges, especially for vulnerable populations such as children, where physiological variation and ethical considerations limit traditional randomized clinical trials (RCT). Special attention will be given to special patient groups where dose manipulations are common, to achieve evidence-based understanding of risk management strategies.

Eligibility Requirements

To meet the eligibility requirements for doctoral education, you must have:

• a master's degree in a relevant field for the project, such as pharmacy, or a similar area that includes education in drug development, or completed at least 240 higher education credits, of which at least 60 at an advanced level including an independent project of at least 15 credits.
• proficiency in English, both spoken and written; personal suitability, motivation, and interest in – as well as experience with – research in the formulation of solid oral dosage forms and quality control are considered merits.
• basic knowledge in pharmacokinetics and modeling, particularly in Open Systems Pharmacology Suite (PK-Sim/MoBi, R-packages), is meritorious.

More information about the eligibility requirements can be found here (https://www.uu.se/medarbetare/vetenskapsomrade/medicin-och-farmaci/utbildning-och-undervisning/utbildning-pa-forskarniva).

The selection of applicants is made by the supervisor in consultation with the department's doctoral education group. The doctoral education committee within the field of medicine-pharmacy will admit the PhD candidate. The selection is based on the qualifications mentioned above, grades in relevant courses, the relevance of the courses to the research area, previous experience of work and research in the area described above. An integrated assessment will be made to hire the most suitable candidate who can succeed in the doctoral education and contribute to a positive development of the research program. Great emphasis will be placed on personal qualities such as analytical ability, accuracy, flexibility, and teamwork.

About the Employment

The employment is temporary, according to HF Chapter 5 § 7. The extent is full-time. Start date by agreement. Place of employment: Uppsala.

Salary placement is according to local guidelines at Uppsala University.

For employment, it is required that the holder is admitted or will be admitted to doctoral education. Regulations for doctoral students can be found in the Higher Education Ordinance Chapter 5 §§1-7 and the university's rules and guidelines here (http://regler.uu.se/). The PhD candidate will primarily devote themselves to their own doctoral education. Other duties at the department, such as teaching and administrative work, may be included within the framework of the PhD position (max 20%), which may also imply that tasks require knowledge of Swedish. Doctoral education normally comprises 4 years of full-time studies, a maximum of 5 years if departmental duties are included.

Application Procedure

The application should include a letter in which the applicant briefly describes themselves and their research interests. The application should also include a CV, copies of degree certificates and transcripts, thesis, and any other documents the applicant wishes to refer to. Please provide contact details for references.

Inquiries about the position can be made to: Professor Albert Mihranyan, email [email protected] (mailto:[email protected]).

For questions regarding the position, Administrative Manager Marina Rönngren, email [email protected] (mailto:[email protected]).

Welcome with your application no later than March 13, 2026, UFV-PA 2026/362.

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of the country's most exciting workplaces.

Read more about our benefits and what it is like to work at Uppsala University here (https://uu.se/om-uu/jobba-hos-oss/).

The employment may be subject to security clearance. A prerequisite for employment is that the applicant is approved during the security clearance.

We kindly decline offers of recruitment and advertising assistance.

Applications are received in Uppsala University's recruitment system.

Union representatives: Saco-S - [email protected] (mailto:[email protected]), Seko - [email protected] (mailto:[email protected]), ST (OFR/S) - [email protected] (mailto:[email protected]).