Vacant job

Job Description

Tissue organization is achieved because the genome encodes for both cell-type identity and extracellular signaling, but how cell types, signaling mechanisms, and transcription factors jointly determine tissue structure is incompletely understood. The Koplev Laboratory is recruiting an outstanding and ambitious postdoctoral researcher in computational biology to pioneer the understanding and modeling of tissue architecture using single-cell and spatial transcriptomics data. The focus will be on developing new computational methods with state-of-the-art machine learning to gain fundamental insights into healthy and diseased human tissues in the heart, cardiovascular system, and gastrointestinal tract. The research will establish spatiotemporal models of human tissue architectures, revealing how niches are formed, change, and malfunction in human organs and diseases. This may include investigating tertiary lymphoid structures in inflammatory diseases, endocrine signaling between organs, comparative niches of stem cells across tissues, or mechanisms of transcriptional regulation such as alternative splicing, depending on the applicant's interests and expertise.

The successful candidate will join an expanding collaborative research group working closely with researchers at the Department of Gene Technology, SciLifeLab, as well as leading international research groups. The role involves developing and conducting primary research projects in computational biology, leading to dissemination and publication in academic journals and conferences. Additionally, the role will support and provide significant operational contributions to scientific excellence and productivity in the research laboratory, as well as help shape and guide students to achieve individual and collective research goals. This offers opportunities for training in scientific leadership for potential application as an independent group leader or senior researcher.

More information: https://www.scilifelab.se/researchers/simon-koplev/ (https://www.scilifelab.se/researchers/simon-koplev/)

Qualifications

Requirements

• A completed PhD degree or a foreign degree assessed as equivalent to a PhD. This qualification requirement must be met no later than the time the employment decision is made.
• Significant research expertise in computational biology methods for single-cell or spatial transcriptomics data.
• Proven scientific excellence, as evidenced by strong scientific publications and a merit list relative to career stage.
• Strong programming skills (Python or R) and familiarity with high-performance computing.

Meritorious Qualifications

• At the final application deadline, no more than three years have passed since the PhD degree or a foreign degree assessed as equivalent to a PhD was awarded.
• A highly creative researcher with broad scientific curiosity.
• Mastery of data visualization and scientific communication.
• Extensive knowledge of relevant machine learning and AI techniques.
• Exceptional collaboration skills.
• Self-motivated individual with the ability to work independently.
• Teaching and mentoring ability or interest in personal development.
• Awareness of diversity and equal opportunity issues, with a particular focus on gender equality.

We welcome applicants with diverse backgrounds and complementary strengths.

We will place great emphasis on personal qualities.

Join KTH

KTH shapes the future through education, research, and innovation. As a leading international technical university, we play an active role in driving and contributing to the transition to a sustainable society. Here, you are offered the opportunity to grow and develop in a creative and dynamic workplace with good working conditions and benefits. Gender equality, diversity, and equal opportunities are quality issues and a clear part of KTH's value system as a university and public authority.

Read more about our benefits and what it is like to work and develop at KTH.

Union Representatives

Contact information for union representatives is available.

Application

You apply via KTH's recruitment system. As an applicant, you are primarily responsible for ensuring your application is complete when submitted.

The application must include:

• CV including relevant professional experience and knowledge.
• A short motivation letter describing why you want to conduct research, your academic interests, and how they relate to your previous studies and future goals. Maximum two pages.
• A copy of your PhD degree certificate. Translations into English or Swedish if the original documents were not issued in either of these languages.

The application must be received by KTH no later than the final application date by midnight, CET/CEST (Central European Time/Central European Summer Time).

About the Position

The position is permanent, but for a maximum of two years.

A postdoctoral position is a time-limited merit-based appointment with a primary focus on research, intended as a first career step after doctoral defense.

Other Information

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