Researcher in Zebrafish Modeling and Genetic Tools

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focused on areas such as cancer, genetic and autoimmune diseases. One of the core ideas at the department is to stimulate translational research and thereby promote closer collaboration between medical research and healthcare. Research is conducted within six research programs: cancer precision medicine, cancer immunotherapy, genomics and neurobiology, molecular tools and functional genomics, neuro-oncology and neurodegeneration, as well as vascular biology. Parts of the activities are also integrated with the departments of oncology, clinical genetics, clinical immunology, clinical pathology, and hospital physics at Uppsala University Hospital. The department has teaching assignments in several program education, independent courses, and international master's programs within the medical faculty. The department has a turnover of approximately 550 million SEK, of which about two-thirds are external research grants. The number of employees is about 400, of which about 100 are doctoral students, and there are a total of over 850 active in the workforce. Please read more about the department's activities here: http://www.uu.se/medarbetare/institution/immunologi-genetik-och-patologi (http://www.uu.se/medarbetare/institution/immunologi-genetik-och-patologi)

Job Description

The position focuses on utilizing zebrafish as a model organism to develop and optimize advanced genetic tools, with significant therapeutic and industrial applications. Key responsibilities include:

1. Pipeline Development and Innovation:
   • Design and establish zebrafish models for the development of advanced genetic tools for high-throughput screening.
   • Implement in vitro and in vivo mutagenesis strategies and fluorescence-based screening workflows using CRISPR/Cas9, Phi-C31 integrase, and FACS.
   • Apply next-generation sequencing technologies to screening workflows.
2. Commercialization and Strategic Growth:
   • Develop patentable genetic tools and optimization pipelines with high commercial potential.
   • Collaborate with internal and external stakeholders to secure partnerships and promote the application of developed technology within academia and industry.
3. Project Management and Delivery:
   • Manage project timelines, documentation, and milestones, ensuring that results are delivered on time.
   • Coordinate interdisciplinary teams and align project outcomes with strategic goals, including publications, patents, and market-ready tools.
4. Communication:
   • Represent the project at conferences and industry events and promote strategic partnerships.
   • Contribute to writing research grants and business proposals to support the project's sustainability and growth.

Qualifications

• PhD in molecular biology, genetics, biotechnology, or a related field.
• Documented experience in zebrafish research, including transgenesis and CRISPR/Cas9-based genome editing.
• Documented expertise in genetic or molecular screening pipelines with high throughput, including mutagenesis and FACS.
• Strong project management skills with documented experience in delivering complex projects on time.
• Excellent communication skills and experience in stakeholder engagement.

Desirable/Preferred Qualifications

• Experience in patenting and commercialization of research results.
• Ability to identify market opportunities and build strategic partnerships.
• Knowledge of bioinformatics tools for library design and data analysis.
• Documented ability to lead interdisciplinary teams and collaborate between academia and industry.
• Experience in grant applications.
• Background in business development or strategic planning in a research or biotech startup environment.
• Scientific and entrepreneurial mindset with strong accuracy and problem-solving skills.

About the Position

The position is permanent, with a probationary period applicable. The scope is full-time. Start date by agreement. Location: Uppsala

For inquiries about the position, please contact: Thomas Juan, [email protected] (mailto:[email protected])

Welcome with your application by December 23, 2025, UFV-PA 2025/3789

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of the country's most exciting workplaces.

Read more about our benefits and what it is like to work at Uppsala University https://uu.se/om-uu/jobba-hos-oss/ (https://uu.se/om-uu/jobba-hos-oss/)

The position may be subject to security clearance. A prerequisite for employment is that the applicant is approved during the security clearance.

We kindly decline offers of recruitment and advertising assistance.

Applications are received in Uppsala University's recruitment system.

Union representatives: Saco-S - [email protected] (mailto:[email protected]), Seko - [email protected] (mailto:[email protected]), ST (OFR/S) - [email protected] (mailto:[email protected])