PhD Candidate in Cancer Precision Medicine

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focused on cancer, autoimmune, and genetic diseases. One of the fundamental ideas at the department is to stimulate translational research and thus a closer collaboration between medical research and healthcare. Research is conducted in cancer precision medicine, cancer immunotherapy, genomics and neurobiology, molecular tools and functional genomics, neuro-oncology and neurodegeneration, as well as vascular biology. Parts of the activities are also integrated with the departments of oncology, clinical genetics, clinical immunology, clinical pathology, and hospital physics at Uppsala University Hospital. The department has teaching assignments in several program educations, independent courses, and international master's programs within the medical faculty and the technical-nature sciences area. The department has a turnover of approximately 500 million SEK, of which just over half is external research grants. The number of employees is about 345, of which about 100 are PhD candidates, and there are a total of over 700 active in the workforce. Please read more about the department's activities here: https://www.uu.se/institution/immunologi-genetik-och-patologi (https://www.uu.se/institution/immunologi-genetik-och-patologi)

Job Responsibilities

You will develop and study cell models for new treatment targets that have undergone loss of heterozygosity in colorectal cancer. You will create genetically modified cancer cells using CRISPR-SELECT and other advanced gene editing methods. You will characterize these models in terms of phenotypes and responses to various drugs used in cancer treatment.

Qualifications

Master's degree in the life sciences field. Documented experience in laboratory work with the culture of human cells.

Information about doctoral education, eligibility requirements, and admission regulations can be found at https://www.uu.se/vetenskapsomrade/medicin-och-farmaci/utbildning/utbildning-pa-forskarniva (https://www.uu.se/vetenskapsomrade/medicin-och-farmaci/utbildning/utbildning-pa-forskarniva). Selection of applicants will be made by the supervisor in consultation with the department's doctoral education group. The doctoral education committee within the field of medicine-pharmacy will admit the PhD candidate. Salary placement will be according to local guidelines at Uppsala University.

For employment, it is required that the holder is admitted or will be admitted to doctoral education. Regulations for doctoral candidates can be found in the Higher Education Ordinance Chapter 5 §§1-7 and the university's rules and guidelines http://regler.uu.se/ (http://regler.uu.se/). The PhD candidate should primarily devote themselves to their own doctoral education. Other duties at the department, such as teaching and administrative work, may be included within the framework of the PhD position (max 20%). Doctoral education normally comprises 4 years of full-time study, a maximum of 5 years if departmental duties are included.

Desirable/meriting

Documented experience in CRISPR-based gene editing.

Regulations for doctoral candidates can be found in the Higher Education Ordinance Chapter 5 §§ 1-7 and at https://www.uu.se/medarbetare/organisation-styrning/regler/ (https://www.uu.se/medarbetare/organisation-styrning/regler/)

About the Position

The position is temporary, according to HF Chapter 5 § 7. The extent is full-time. Start date by agreement. Location: Uppsala

Inquiries about the position can be made to: Tobias Sjöblom, 018-4715036, tobias.sjoblom@igp.uu.se

Welcome with your application by April 10, 2025, UFV-PA 2025/382

Uppsala University is a broad research university with a strong international position. The ultimate goal is to conduct education and research of the highest quality and relevance to make a difference in society. Our most important asset is all 7,600 employees and 53,000 students who, with curiosity and commitment, make Uppsala University one of the most exciting workplaces in the country.

Read more about our benefits and what it is like to work at Uppsala University https://uu.se/om-uu/jobba-hos-oss/ (https://uu.se/om-uu/jobba-hos-oss/)

The position may be subject to security clearance. A prerequisite for employment is that the applicant is approved during the security clearance.

We kindly decline offers of recruitment and advertising assistance.

Applications are received in Uppsala University's recruitment system.