PhD Position in Advanced Lipid-Based Cellular Membrane Mimicry and Interaction Studies

We are seeking a highly motivated PhD candidate to join us in advancing lipid-based mimics of cellular membranes. This project explores surface-assisted lipid self-assembly using advanced tools such as QCM, SPR, and optical microscopy to investigate interactions between biological nanoparticles, including viruses and drug delivery vehicles, with sophisticated membrane models. This is an opportunity to develop your expertise in biophysics using cutting-edge facilities, collaborate with experts in biological, medical, and pharmaceutical sciences, and contribute to a rapidly expanding field. You will be working in a supportive academic environment that fosters innovation and growth.

Project Overview

The primary aim of this biophysics-based project is to elucidate the interactions between biological nanoparticles and cellular membranes, with a particular focus on the influence of membrane composition. Through collaboration with researchers in pharmaceutical, biological, and medical disciplines, the work leverages cell-membrane mimics and lipid self-assembly to advance diagnostics, drug screening, drug delivery, and vaccine development. By bridging applied physics, nanoscience, chemistry, and biology, the project contributes to innovative analytical approaches and deep biophysical insights relevant to medicine.

About the Research Group

The Biophysics group, part of the Nano and Biophysics division, specializes in translational life-science research, emphasizing interdisciplinary collaboration with biological and medical settings. Our team develops surface-based bioanalytical microscopy tools and microfluidics for the study of cell-membrane mimics, membrane-protein analysis, and biological nanoparticle interactions. By integrating surface-sensitive microscopy, microfluidic platforms, and nanofabrication, we aim to improve diagnostic techniques and pharmaceutical applications, particularly in nanoparticle-mediated drug delivery systems.

Major Responsibilities

As a PhD candidate, your primary responsibilities will include:

• Conducting independent research and developing scientific concepts.
• Communicating research results through written and verbal presentations.
• Engaging in bioanalytical laboratory work, image analysis, and collaborative projects with biological and medical research groups.
• Participating in undergraduate teaching and other duties, comprising up to 20% of your working hours.
• Taking part in international exchanges to broaden your research experience.

Learn more about doctoral studies at Chalmers here (https://www.chalmers.se/en/education/doctoral-studies/Pages/default.aspx).

Qualifications

Required:

• MSc in Physics or Biophysical Chemistry (or equivalent), corresponding to at least 240 higher education credits.
• Experience in wet chemistry, biointerface analytics, and optical microscopy.
• Proficiency in written and spoken English.
• Familiarity with MATLAB.

Meritorious:

• Experience conducting independent laboratory research within a research group.
• Proficiency in image analysis.

Contract Terms

This is a full-time temporary position, limited to a maximum of five years.

What We Offer

Chalmers provides a cultivating and inspiring working environment in the coastal city of Gothenburg. Read more about working at Chalmers and our benefits for employees.

Chalmers aims to actively improve our gender balance. We work broadly with equality projects, for example the GENIE Initiative on gender equality for excellence. Equality and diversity are substantial foundations in all activities at Chalmers.

Application Procedure

Applications must be written in English and submitted as PDF files. Each file should not exceed 40 MB. Please note that zip files are not supported.

Required documents:

• CV (File name: CV, Family Name):
  • Detailed curriculum vitae.
  • Information about previous employment, leadership qualifications, and positions of trust.
  • Two references we may contact.
• Personal letter (File name: Personal Letter, Family Name):
  • 1–3 pages introducing yourself.
  • A description of relevant experience (education, thesis work, and, if applicable, other research activities).
  • A statement of your future goals and research interests.
• Additional documents:
  • Copies of your bachelor’s and/or master’s thesis.
  • Attested copies of educational transcripts, grades, and certificates (e.g., TOEFL test results).

Submit your application using the button at the bottom of the application page. Incomplete applications or those submitted via email will not be considered.

Application deadline: 16 March 2025

Contact for Questions:

Fredrik Höök
Email: [email protected] (mailto:[email protected])
Phone: +46-708-951239

Chalmers declines to consider all offers of further announcement publishing or other types of support for the recruiting process in connection with this position.

Chalmers University of Technology in Gothenburg conducts research and education in technology and natural sciences at a high international level. The university has 3100 employees and 10,000 students, and offers education in engineering, science, shipping and architecture. With scientific excellence as a basis, Chalmers promotes knowledge and technical solutions for a sustainable world. Through global commitment and entrepreneurship, we foster an innovative spirit, in close collaboration with wider society. Chalmers was founded in 1829 and has the same motto today as it did then: Avancez – forward.