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Postdoctoral Researcher in Molecular Modeling of Ion Channels

Kungliga Tekniska Högskolan

Stockholms län, Stockholm

Previous experience is desired

12 days left
to apply for the job

Job Description

Ion channels are vital for life among organisms, and a sophisticated understanding of their function is absolutely necessary for basic, biomedical, and applied research. The overarching goal of the proposed project is to develop ion channel activators and inhibitors. Unmet specificity needs will be addressed by targeting subtype- and conformation-specific properties, thereby limiting side effects. The focus will be on Kv7 channels, which are linked to a range of serious neurological disorders, including epilepsy, sleep disorders, and autism.

The postdoctoral researcher will perform molecular modeling and molecular dynamics simulations of these channels bound to various modulators. The results will be integrated into a KAW-funded collaborative project with four other principal investigators conducting cryo-electron microscopy, electrophysiology, behavioral experiments, and machine learning.

Qualifications

Requirements

  • A completed PhD degree or a foreign degree assessed as equivalent to a PhD. This eligibility requirement must be met no later than the time the employment decision is made.
  • Experience with molecular dynamics simulations.
  • Experience working in collaborative environments.
  • Scientific proficiency.
  • Awareness of diversity and equal treatment issues, with a particular focus on gender equality.
  • Ability to work independently.

Merits

  • PhD degree or a foreign degree assessed as equivalent to a PhD awarded no more than three years prior to the application deadline.
  • Teaching ability.
  • Collaborative skills.
  • Experience with enhanced sampling simulations and coarse-grained force fields.
  • Experience with biological systems, including membrane proteins.

We will place great emphasis on personal qualities.

Join KTH

KTH shapes the future through education, research, and innovation. As a leading international technical university, we play an active role in driving and contributing to the transition to a sustainable society. Here, you are offered the opportunity to grow and develop in a creative and dynamic workplace with good working conditions and benefits. Gender equality, diversity, and equal opportunities are quality issues and a clear part of KTH's values as a university and a government agency.

Read more about our benefits and what it is like to work and develop at KTH.

Union Representatives

Contact details for union representatives.

Application

You apply via KTH's recruitment system. As an applicant, you are primarily responsible for ensuring your application is complete when submitted.

The application should include:

  • CV including relevant professional experience and knowledge.
  • A concise statement on why you wish to conduct research, your academic interests, and how they relate to your previous studies and future goals. Max 2 pages.

The application must be received by KTH no later than midnight on the application deadline, CET/CEST (Central European Time/Central European Summer Time).

About the Position

The employment is permanent, but for a maximum of three years.

A postdoctoral position is a time-limited merit-based appointment with a primary focus on research, intended as a first career step after the PhD defense.

Other Information

For information on the processing of personal data in connection with recruitment, please see KTH's policy.

Some positions at KTH may be classified for security reasons. If this applies to this specific position, a security check will be conducted on the applicant in accordance with the Security Protection Act (2018:585) with consent. In such cases, approval after the security check is a prerequisite for employment.

We decline direct contact with staffing and recruitment agencies as well as sellers of job advertisements.

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