Vacant job

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development, and commercialization of prescription medicines for some of the world's most serious diseases.

Pharmaceutical Technology and Development (PT&D) is the organization within Operations AstraZeneca that turns brilliant science into medicines that help millions of people. In the Digital Science Organisation (DSO), which sits within PT&D, we focus on the development of digital strategy, new tools, and technologies. We work collaboratively with functions, IT, and external partners to transform the way we deliver drug substances and drug products. The DSO has recently centralized modeling and simulation skills to create a strategic global team of experts covering a wide range of modeling and simulation expertise, with members based in Gothenburg, Sweden, and Macclesfield, UK.

The Role

In this role, you will work collaboratively with a variety of scientific specialists and project managers across a global organization to optimally deliver engineering modeling solutions and play a key role in crafting and driving the modeling and simulation strategy.

Responsibilities:

• Build strong working relationships with team members and colleagues across PT&D to support the application of modeling and simulation.
• Work collaboratively with project teams and experimentalists from different backgrounds to identify modeling and simulation opportunities, strategically direct experimentation, and translate pharmaceutical process problems into appropriate mechanistic/first principles models.
• Coach and upskill process engineers by delivering training/workshops and sharing good practices of using modeling and simulation tools in pharmaceutical development.
• Support defining and establishing model/data standards, workflows for model verification and validation, data collection, experiment conditions, and sampling, etc. Develop, verify, validate, implement, and document modeling and simulation workflows to be used by the wider scientific community.
• Drive and champion the organizational digital transformation by developing automated, documented, and verified workflows to make simulation tools accessible to a wider community of process engineers, chemists, and pharmacists.
• Keep abreast of global developments in your area by attending relevant events such as conferences, webinars, and workshops and being an active member of relevant networks and working groups.
• Ensure access to state-of-the-art tools and technologies through engaging in pre-competitive collaborative projects, initiatives with academia and software vendors, etc.

Essential Skills and Qualifications:

• A solid scientific background with a PhD or MSc/MEng in chemical engineering, physics, chemistry, mathematics, or related subject area, ideally with a specialization in process modeling.
• A few years of post-graduate industrial work experience in a relevant field.
• A solid knowledge of the science behind process models and experience developing and applying process models for the development of industrial products and processes.
• Ability to provide scientific leadership, coaching, and mentorship for less experienced scientists and for the wider PT&D community.
• Ability to select an appropriate modeling approach and build mathematical models of physical/chemical phenomena and solve them using appropriate coding tools.
• Proven strong expertise in relevant programming and scripting languages, e.g., Matlab, Python, or similar, and a willingness to learn.
• Experience using simulation tools including gPROMS, DynoChem, Aspen, Ansys Fluent/CFX, Ansys Rocky, etc.
• Strong collaboration, communication, influencing, and networking skills.
• Cultural awareness.

Desirable Skills and Qualifications:

• Considerable experience in the pharmaceutical/biopharmaceutical/food/cosmetics and personal care/fast-paced consumer goods industry.
• A broad knowledge of process equipment and process technology.
• Ability to proactively identify and apply novel modeling approaches to deliver value in the development and manufacturing of pharmaceutical drug products.
• Postdoc research in relevant modeling and simulation subjects.
• Track record of scientific publications in the modeling and simulation area.

At AstraZeneca, we're dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There's no better place to make a difference to medicines, patients, and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development.

Join us in this great opportunity! Apply with your CV and cover letter no later than April 1st, 2025!