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Subject area

Single-cell genomics and functional imaging of kidney epithelial injury

Subject area description

The project aims to develop and apply novel experimental methods to study functional heterogeneity in proximal tubular epithelial cells (PTECs) during kidney injury. By combining direct measurements of albumin reabsorption with single-cell transcriptomics, the project seeks to identify molecular programs underlying epithelial dysfunction and to discover targetable pathways relevant to kidney disease.

Duties

The successful candidate will lead experimental work across multiple PTEC injury models, including toxic, metabolic, inflammatory, and hypoxia–reoxygenation stress. Key tasks include functional uptake assays using fluorescently labelled albumin, cell and tissue imaging, preparation of single-cell RNA sequencing libraries, data generation from primary human PTECs and acute kidney slices, and close collaboration with computational researchers for downstream analysis. Validation of candidate pathways in tissue slices will be an additional component of the work.

Eligibility

The eligibility criteria for employing teaching staff are set out in Chapter 4 of the Higher Education Ordinance and in the Appointment Procedure for Teaching Posts at the University of Gothenburg.

To be eligible for appointment as a postdoc, the applicant is required to have a doctoral degree, a doctoral degree in art or a foreign degree that is deemed to be equivalent to a doctoral degree. This eligibility requirement must be met before the employment decision is made.

In the first instance, those who have completed their degree no more than three years prior to the end of the application period shall be considered. Those who have completed their degree more than three years prior to the end of the application period may also be considered in the first instance if special grounds exist. Special grounds relate to leave of absence due to illness, parental leave, commissions of trust within union organisations, service within the defence services or other similar circumstances, as well as clinical service or service/assignment relevant to the subject area.

Assessment criteria

The ideal candidates should have:

• PhD in Molecular or Cell Biology, or a related life science discipline
• Experience in cell-based assays and tissue culture
• Experience with molecular biology techniques (RNA extraction, qPCR, NGS library preparation)
• Experience with microscopy techniques, and analysis tools (e.g. Fiji)
• Knowledge of single-cell RNA sequencing methods
• Experience with functional assays in epithelial cells or kidney-related models
• Experience with FACS
• Experience analyzing high-dimensional biological data (Python)
• Ability to work independently, plan experiments, and troubleshoot
• High level of motivation, accuracy, and organizational skills
• Fluency in English

Regulations for the evaluation of qualifications for academic positions are given in Chapter 4, Section 3 - 4 of the Higher Education Ordinance.

Employment

The employment is full time and temporary, two years with the possibility of one year's extension, with placement at the Institute of Biomedicine. First day of employment as agreed.

Selection process

Help for applicants.

Contact information

If you have any questions about the position, please contact Dr. Joan Camuñas Soler: [email protected] (mailto:[email protected])

Unions

Union representatives at the University of Gothenburg can be found here: https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande (https://www.gu.se/om-universitetet/jobba-hos-oss/hjalp-for-sokande)

Application

Submit your application via the University of Gothenburg’s recruitment portal by clicking the “Apply” button. It is your responsibility to ensure that the application is complete as per the vacancy notice, and that the University receives it by the final application deadline.

The application should contain:

• A short statement describing the candidate’s training, interests and future goals as well as motivation to apply for this position.
• Curriculum Vitae
• Proof of completed PhD
• Contact details of two references

Applications must be received by: 2026-02-04

Information for International Applicants

Choosing a career in a foreign country is a big step. Thus, to give you a general idea of what we and Gothenburg have to offer in terms of benefits and life in general for you and your family/spouse/partner please visit:

• https://www.gu.se/en/about-the-university/welcome-services (https://www.gu.se/en/about-the-university/welcome-services)
• https://www.movetogothenburg.com/ (https://www.movetogothenburg.com/)

The University works actively to achieve a working environment with equal conditions, and values the qualities that diversity brings to its operations.

Salaries are set individually at the University.

In accordance with the National Archives of Sweden’s regulations, the University must archive application documents for two years after the appointment is filled. If you request that your documents are returned, they will be returned to you once the two years have passed. Otherwise, they will be destroyed.

In connection to this recruitment, we have already decided which recruitment channels we should use. We therefore decline further contact with vendors, recruitment and staffing companies.