Vacant job

The Department of Molecular Biosciences, Wenner-Gren Institute (MBW) conducts experimental basic research in molecular cell biology, integrative biology, and infection and immunobiology. The research environment is characterized by modern and advanced methodology and has a strong international profile. MBW is one of the larger departments within the Faculty of Science at Stockholm University, with over 30 research groups and approximately 180 employees, including 65 doctoral students. More information about us can be found at: Department of Molecular Biosciences, Wenner-Gren Institute (#).

Field of Study

This doctoral position is within RNA biology, focusing on brain development and RNA editing. The dissertation work will be carried out in the laboratory led by Dr. Eduardo A. Sagredo at MBW. Our research aims to elucidate the role of RNA modifications in various processes during the RNA lifecycle, such as RNA localization and RNA stability/degradation. The successful candidate will work on a fully funded project aimed at systematically investigating the relationship between RNA editing and subcellular mRNA localization during neuronal differentiation and brain development, using state-of-the-art transcriptome-wide sequencing and functional methods. The successful candidate will be part of a dynamic, internationally oriented research environment at the intersection of RNA biology, epitranscriptomics, and neuroscience. The project offers training in current and novel transcriptomic and cell biological methods, as well as models for neuronal differentiation and animal studies (mice).

Admission Requirements

To be admitted to doctoral studies, the applicant must have basic and specific eligibility. Eligibility must be met by the application deadline.

You have basic eligibility if you have completed an advanced level degree, or completed course requirements of at least 240 higher education credits (HEC), including at least 60 HEC at advanced level, or otherwise acquired substantially equivalent knowledge within or outside the country.

Specific eligibility is described in the study plan for doctoral studies in the field of molecular biosciences. You meet the specific eligibility requirements if you have at least 120 higher education credits in molecular biology, biology, chemistry, or equivalent at the first-cycle level, and at least 60 higher education credits at the second-cycle level in molecular biosciences or equivalent, including at least 30 higher education credits consisting of an independent degree project.

Selection

Selection among applicants is made with regard to the ability to benefit from education at the doctoral level. Criteria used to assess this ability include:

• Documented knowledge in a relevant research area, and a research plan/project plan for the intended project (max 2 pages) should be included in the application.
• Strong interest in interdisciplinary technological development related to RNA biology, genomics, and/or proteomics.
• Practical experience in molecular biology, proteomics, and/or genomics with a focus on interpreting biological data and experimentally testing hypotheses (e.g., Western Blotting, immunoprecipitation and immunofluorescence, qPCR, RNA-seq, and/or CLIP-related methods).
• Experience with cell culture and mouse work is considered highly meritorious.
• Basic knowledge of programming languages (such as bash, R, or Python) for handling NGS datasets is considered meritorious.
• Independence in analyzing and organizing previous scientific work.
• Problem formulation and precision in previous scientific work and in the research plan.
• Previously demonstrated ability to meet specified timeframes.
• Methodological and scientific maturity, describing independence, initiative, and teamwork skills.
• Strong written and oral communication skills in English.

Admission regulations for higher education at the doctoral level at Stockholm University.

About the Position

We offer a fixed-term position as a doctoral student according to Chapter 5 of the Higher Education Ordinance (1993:100). The period of employment may not be longer than what corresponds to full-time doctoral education over four years. As a doctoral student, you should primarily devote yourself to your own doctoral education, but the employment may include work with education, research, and administration to a limited extent (maximum 20%).

A new appointment as a doctoral student is valid for at most one year; the appointment is then renewed for at most two years at a time.

Stockholm University strives to be a workplace free from discrimination and to provide equal rights and opportunities for everyone.

Contact

Further information is provided by Doctor Eduardo A. Sagredo, [email protected].

Application

You apply for the doctoral position via Stockholm University's recruitment system. Attach a cover letter and CV, as well as the attachments requested in the application form. As an applicant, you are responsible for ensuring that the application is complete in accordance with the advertisement and that it is submitted to the university no later than the application deadline.

Instructions for applicants can be found on the webpage: applying for a position (#).

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